Liquid Premix A+Se

A+Se is highly recommended to be used as a combination of vitamins and amino-acids with selenium in the period of increasing demand in nutrients, especially for highly-performance and young animals, during stress situations.

Target Species:

Poultry;Cattle; Horses;Calves;Foals, Pigs; Goats;Sheep

Recommended Usage:

Oral, during 2-3 days.   Repeat if necessary

Before usage, shake it properly. For poultry dissolve at least 100 ml not less than in 10 liters of water. Bring to the required volume with drinking water. Do not use in pure form. Opened package use immediately.

Storage & Precautions:

Keep in a cool and dry place.

Shelf Life: 18 months

Introduction and Core Purpose

LIQUID PREMIX A+Se is a specialized nutritional intervention formulated to address acute and transitional periods where an animal's dietary intake is insufficient to meet its elevated physiological demands. It is a synergistic blend of essential vitamins, key amino acids, and the critical trace mineral selenium, presented in a highly bioavailable liquid form. The product is not intended for routine, long-term supplementation but rather functions as a strategic tool to bolster metabolic resilience, support rapid recovery, and maintain productivity during predictable and unpredictable challenges. Its design caters to the modern needs of intensive livestock, poultry, and equine management, where optimizing health during stress directly impacts welfare and economic outcomes.

Mechanism of Action: Addressing the Nutrient Gap

During periods of stress, high performance, or rapid growth, an animal's metabolism shifts dramatically. Stressors trigger the release of hormones like cortisol, which increases the breakdown of body proteins (catabolism) to provide energy, simultaneously suppressing immune function and elevating the production of damaging free radicals (oxidative stress). Concurrently, the requirements for vitamins, which act as metabolic catalysts, and amino acids, the building blocks for repair and growth, can surpass the levels available from standard feed.

Amino Acids: Provide readily available substrates to counteract muscle wasting, support the synthesis of immunoglobulins and acute-phase proteins for immune defense, and facilitate tissue repair.

Vitamins: Function as indispensable coenzymes in energy metabolism (B-vitamins), antioxidant systems (Vitamins A, E), and cellular repair processes. They ensure that the energy liberated from feed is utilized efficiently for maintenance and recovery.

Selenium: This is a cornerstone of the product's efficacy. Selenium is incorporated into the enzyme glutathione peroxidase, one of the body's primary antioxidant defenses. It neutralizes harmful lipid peroxides, protecting cell membranes—especially in muscles and tissues under duress—from oxidative damage. This is crucial during heat stress, disease challenge, or physical exertion.

Primary Application Scenarios

Metabolic and Production Stress: This includes the periparturient period in dairy cows (around calving), peak lactation, the final finishing stage in beef and pigs, and the laying peak in poultry. These phases represent the pinnacle of nutrient output, where supporting the liver, musculoskeletal system, and reproductive tract is vital to prevent conditions like ketosis, poor milk quality, or skeletal disorders.

Developmental and Transitional Stress: Key moments such as weaning in piglets, calves, and foals; the first week post-hatch in chicks; and moving to new housing. These events combine psychological stress with a drastic change in diet and social structure, frequently leading to reduced feed intake and increased disease susceptibility. A+Se helps bridge the nutritional gap and supports the developing immune system.

Environmental and Operational Stress: Transportation, extreme weather (heat or cold), regrouping, vaccination reactions, and recovery from illness or surgery. These events reliably induce a stress response. Prophylactic or immediate use of A+Se for 2-3 days can enhance the animal's capacity to cope, reducing the severity and duration of the negative impacts on performance and health.

Support for High-Performance and Young Animals: As stated, these groups are inherently at higher risk. Young animals have immature antioxidant systems and high growth demands, while high-performance animals operate at the edge of their metabolic capacity. A+Se provides a targeted nutritional buffer.

Species-Specific Application Guidance

For all species, the product is administered orally via drinking water.

Poultry:  "Shake it properly" . A minimum of 100 mL must be dissolved in no less than 10 liters of water initially. This concentrated solution is then added to the main drinking water line to achieve the final required volume for the flock. This two-step dilution ensures even distribution and prevents the risk of localized high concentrations that could lead to inconsistent intake or palatability issues. "Do not use in pure form" is an absolute safety imperative.

Ruminants & Equines (Cattle, Calves, Goats, Sheep, Horses, Foals): The premix can be diluted in the daily drinking water supply. For individual or small group treatment, it can be administered as a drench following proper dilution. Ensuring adequate water intake is key to delivering the correct dose.

Pigs: Can be administered via the watering system. During critical times like weaning, when water intake may be more consistent than feed intake, this method ensures all animals receive support.

Administration Protocol and Rationale

The recommended course of 2-3 days is scientifically pragmatic. It is designed to provide an intensive "nutrient surge" during the acute phase of the challenge. Extending use beyond this without veterinary advice is unnecessary for most transient stress events and may disrupt the balance of other nutrients in the complete diet. The instruction "Repeat if necessary" allows for flexibility in prolonged stress situations, such as an extended heatwave or a slow recovery from disease, but such decisions should be informed by observed animal condition.

The mandate to use an opened package immediately is non-negotiable. Once opened, the liquid is exposed to air, leading to potential oxidation of sensitive vitamins and selenium, reducing potency and risking the formation of degraded compounds.

Storage and Concluding Best Practices

Storing the product in a cool and dry place protects its stability from the degrading effects of heat, light, and moisture. In practice, this application guide underscores that LIQUID PREMIX A+Se is most effective when used as part of a proactive management strategy. Identifying periods of predictable stress and administering the premix just prior to or at the onset of the challenge yields superior results compared to a reactive approach after performance has already declined. By strategically supporting the animal's internal biochemistry during these critical windows, the product aids in maintaining homeostasis, welfare, and profitable production.